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Cyclopentadecanolide

RESTRICTION
CAS
106-02-5
EC
Material type
other
Canonical source
document derived
chemicals · No. 811

Arctander monograph

Perfume and Flavor Chemicals, page 335.

BASEtenacity · highpower · strongG.R.A.S.FEMA 2840
animalmuskysweet
MW
240.39
BP
280°C
MP
36.5°C
Sp.Gr.
Refractive n
Rotation
Appearance

Solid, colorless, crystalline mass, melting at 36-37°C to a colorless, viscous oil.

Odor

Delicately animal, musky and sweet, extremely tenacious odor of outstanding uniformity.

Flavor

Cyclopentadecanolide gives highly interesting effects when applied to certain flavors, e.g. alcoholic beverages, dentifrice flavors etc.

Uses in perfumery

Common use level in the perfume oil is about 0.1 to 0.49%. The fixative effect is absolutely unusual in that it is not a physical fixation, but a true fixative and mellowing effect at incredibly low concentration of usage.

Uses in flavor

Concentration in such flavors may be about 0.02 to 1.50 ppm calculated upon the finished consumer product. However, it should be kept in mind that dentifrices are flavored at extremely high concentration (about 1%) and it may therefore give an underestimated evaluation of the power of this Lactone.

Production

1) by oxidation of Cyclopentadecanone. 2) from linear polyesters of Pentadecanoic acid.

Document-derived

IFRA restrictions

CategoryKindMax %NotesSource
Category 1Max %0.42%
DOC
Category 2Max %0.13%
DOC
Category 3Max %2.5%
DOC
Category 4Max %2.4%
DOC
Category 5AMax %0.6%
DOC
Category 5BMax %0.6%
DOC
Category 5CMax %0.6%
DOC
Category 5DMax %0.2%
DOC
Category 6Max %1.4%
DOC
Category 7AMax %4.8%
DOC
Category 7BMax %4.8%
DOC
Category 8Max %0.2%
DOC
Category 9Max %4.6%
DOC
Category 10AMax %4.6%
DOC
Category 10BMax %17%
DOC
Category 11AMax %0.2%
DOC
Category 11BMax %0.2%
DOC
Category 12No restrictionNo Restriction
DOC

Compliance-support only. Values resolved from the current IFRA corpus; each row cites the document excerpt it came from. Not a substitute for a qualified safety assessor.

IFRA Annex I

Found naturally in

Natural complex substances (NCSs) in which this material typically occurs.

NCSBotanicalTypical %
Angelica Seed OilAngelica archangelica L.1.6%
Galbanum gumFerula spp.0.01%
Identity
Aliases · 24
106-02-5Cyclopentadecanolide15-Hydroxypentadecanoic acid, Lactone15-Hydroxypentadecanoic acid, ω-lactone4-Oxy-tetradecane carbonic acid, LactoneAngelica lactoneCyclopentadecanolid SupraExaltexExaltex (commercial name)ExaltolideExaltolide (commercial name)FortolideMacrolideMacrolide (commercial name)MuscolactonMuscolideMuskalactoneomega-PentadecalactoneOxacyclohexadecan-2-onePentadecalactonePentadecanolidePentalideThibetolideω-Pentadecalactone
Compliance note. Restriction data is sourced directly from IFRA publications and preserved with its document excerpt. Perfume Foundry is a compliance-support tool — not a substitute for a qualified safety assessor (CPSR / PIF).