Iso-Butyl Quinoline (CAS 65442-31-1) is a synthetic aroma chemical known for its distinctive and complex scent profile, often described as having a warm, slightly animalic, and leathery character. In perfumery, it is typically used to add depth and richness to compositions, particularly in oriental and woody fragrances. Its unique olfactory properties make it suitable for use in both fine fragrances and personal care products, where it can enhance the overall scent experience. Iso-Butyl Quinoline is often positioned in the base notes of a formula, where it can contribute to the longevity and persistence of the fragrance. As with many synthetic aroma chemicals, it is important to consider safety and regulatory aspects when formulating with Iso-Butyl Quinoline. While specific IFRA restrictions may apply, it is advisable for perfumers to consult the latest guidelines and safety data to ensure compliance and safe usage in their formulations. — AI-generated summary, 2026-09-02.
A powerful, dry leather note with a distinctly green, almost bitter earthy edge reminiscent of tobacco and old books. Very tenacious and diffusive, with a slightly animalic, oily quinoline character that dominates blends even at trace levels.AI · claude-opus-4-7
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Other ingredients whose composition declares this material as a constituent. The percentage shown is the supplier-declared concentration in that parent.
| Ingredient | % | Range |
|---|---|---|
| PYRALONE 10% | — | — |
Perfume and Flavor Chemicals, page 220.
Colorless, slightly oily liquid
Insoluble in water, soluble in alcohol and oils
Powerful earthy-tarry-mossy odor, at the same time sweet and dry, root-like
Used in perfumery as a modifier for other isomers
Produced from secondary-Butyl aniline and Acrolein, followed by cyclization and oxidation