Chloroxylenol, with the CAS number 88-04-0, is a synthetic aroma chemical commonly used in perfumery for its antiseptic and disinfectant properties. It has a phenolic character, which can impart a fresh, medicinal note to fragrance compositions. In perfumery, Chloroxylenol is often utilized in lower concentrations, typically as a supporting note rather than a primary ingredient, due to its strong and distinctive scent profile. It can be found in formulations aimed at creating clean, fresh, or clinical olfactory experiences. While it is valued for its functional properties, it is important to note that Chloroxylenol is subject to regulatory scrutiny, particularly regarding its safety in cosmetic applications. As with many synthetic compounds, it is advisable for formulators to be aware of any potential restrictions or guidelines set forth by regulatory bodies such as IFRA, as well as to consider consumer sensitivities to phenolic compounds. Overall, Chloroxylenol serves a specific role in fragrance formulations, balancing its unique scent characteristics with safety considerations. — AI-generated summary, 2026-09-02.
Chloroxylenol (PCMX) has a sharp, medicinal-phenolic odor reminiscent of Dettol antiseptic — dry, slightly tar-like with a cool camphoraceous edge. Not a traditional perfumery material; it reads as clinical and disinfectant rather than aromatic.AI · claude-opus-4-7
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Perfume and Flavor Chemicals, page 257.
Colorless crystals
Soluble in water, alcohol and oils
Mild-phenolic type odor, rather dry but weaker than that of phenol or cresol
Produced from meta-Xylenol by chlorination with Cl2 or SO2Cl2