Gamma-Dodecalactone, with CAS number 2305-05-7, is a synthetic aroma chemical known for its creamy, fruity, and coconut-like scent profile. It is often used in perfumery to impart a smooth, milky character to compositions, making it a popular choice in gourmand and floral fragrances. This compound typically sits in the base or heart of a formula, where it can enhance the overall richness and complexity of the scent. Gamma-Dodecalactone is valued for its ability to blend well with other ingredients, particularly those that are fruity or floral, and it can help to round out sharper notes. As with many synthetic aroma chemicals, it is important to consider safety and regulatory aspects when formulating with Gamma-Dodecalactone. While specific IFRA restrictions may apply, it is advisable for perfumers to consult the latest guidelines and safety data to ensure compliance and safe usage in cosmetic products. — AI-generated summary, 2026-09-02.
A rich, creamy peach-skin aroma with a soft, milky-lactonic character. Opens with a ripe, juicy fruitiness that settles into a waxy, slightly coconut-like sweetness with a suede-smooth texture.AI · claude-opus-4-7
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Perfume and Flavor Chemicals, page 449.
Colorless oily liquid.
Insoluble in water, soluble in alcohol and oils, poorly soluble in propylene glycol.
Fatty-peachy, somewhat musky odor, fattier than undecanolide.
Used in flavor compositions, mainly in butter, butterscotch, coconut, tutti-frutti, maple, nut, peach, pineapple, etc.
Finds some use in perfume compositions for fatty-fruity topnotes and long tenacity, e.g. in heavy floral fragrances. It is also used in combination with newer synthetic musks to produce exceptional tenacity and lasting sweetness in powdery and in floral types.
1) from 4-Hydroxy dodecanoic acid by lactonization. 2) from methyl acrylate plus octanol with a catalyst.