Methyl Nicotinate is a synthetic aroma chemical known for its unique and complex scent profile, which is often described as fresh, green, and slightly floral with a hint of spiciness. It is primarily used in perfumery to impart a bright and uplifting character to fragrances, making it a popular choice in both floral and green compositions. Methyl Nicotinate can be found in various fragrance types, including colognes and eau de toilettes, where it typically serves as a top note or a supporting note that enhances the overall freshness of the scent. In terms of safety and regulatory considerations, Methyl Nicotinate is subject to certain restrictions under IFRA guidelines, particularly regarding its use in cosmetic formulations. As with many synthetic aroma chemicals, it is important for formulators to be aware of potential allergenic properties and to ensure compliance with relevant safety standards. Overall, Methyl Nicotinate is valued for its ability to add a distinctive and refreshing quality to fragrance blends. — AI-generated summary, 2026-09-02.
Methyl nicotinate has a peculiar, dry earthy-nutty character with distinct tobacco and slightly medicinal facets. In dilution it lends a warm, slightly balsamic and roasted quality reminiscent of pyridine-adjacent naturals like tobacco absolute and osmanthus. Used sparingly it adds naturalistic depth to floral and tobacco accords.AI · claude-opus-4-7
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Perfume and Flavor Chemicals, page 913.
White crystals.
Soluble in water, propylene glycol, alcohol and oils.
Warm, but nauseating, sweet-herbaceous odor with mildly tobacco-like notes and moderate tenacity.
This ester has found limited use in perfume compositions for reasons similar to those justifying the use of Piperidine, etc. in certain floral and floral-Oriental bases, flower absolute imitations, etc.
It may be interesting to note then, that Pyridine itself is permitted for use in flavor compositions in the U.S.A.
1) from Tetramethylammonium nicotinate by heating. 2) from Nicotinyl chloride hydrochloride and methanol in presence of pyridine.