Piperitone, with CAS number 89-81-6, is a synthetic aroma chemical known for its minty, fresh, and slightly spicy character. It is commonly used in perfumery to impart a cooling effect and is often found in compositions that aim to evoke freshness, such as in fragrances for personal care products and household items. Piperitone typically sits in the top to middle notes of a formula, where its bright and invigorating qualities can enhance the overall scent profile. In addition to its olfactory contributions, piperitone is also noted for its potential allergenic properties, which necessitates careful consideration in formulation, particularly in products intended for sensitive skin. As with many synthetic aroma chemicals, it is important for formulators to be aware of any regulatory guidelines or restrictions that may apply, including those set forth by IFRA, to ensure compliance and safety in cosmetic applications. — AI-generated summary, 2026-09-02.
A fresh, minty-camphoraceous aroma chemical with a cool herbal edge reminiscent of pennyroyal and peppermint. Slightly medicinal and green, with a dry aromatic character that sits between mint and eucalyptus.AI · claude-opus-4-7
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Perfume and Flavor Chemicals, page 1150.
Colorless liquid.
Practically insoluble in water, soluble in alcohol and oils.
Powerful, fresh-minty-camphoraceous odor. The material may turn darker yellow and its odor become more tobacco-herbaceous upon ageing.
This material has found some use in perfume compositions, mainly in masking odors for industrial purposes, inexpensive room-fresheners, etc.
The cyclic ketone is more commonly used in flavor compositions, particularly in spice complexes with Caraway, Estragon, etc., and in fruit complexes, mint flavors, etc.
1) by isolation from Japanese Mint oil (dextro-Piperitone). 2) by isolation from Eucalyptus dives oil (laevo-Piperitone). 3) by hydrogenation of Diosphenol. 4) by reduction of 5-Methyl-2-iso-propylanisole with Sodium in liquid Ammonia. 5) laevo-Piperitone can also be produced from laevo-beta-Pinene via 1-Limonene, by hydrogenation to 1-Carvomenthene, and via 4 further intermediate steps to the title material.