Musk Xylene (Trinitro-tertiary-butyltoluene) is a classic nitro musk with a sweet, warm, powdery-musky character. It has a soft ambery-animalic undertone and a rounded, slightly balsamic body that lends fixative depth to florals and orientals. Now globally banned in fragrance due to bioaccumulation and toxicity concerns.AI · claude-opus-4-7
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Perfume and Flavor Chemicals, page 1346.
Yellowish needle-like crystals.
Moderately soluble in alcohol and most oils, almost insoluble in water.
Sweet, but rather coarse, musky odor of good tenacity.
This Nitromusk is included mainly for academic and historic reasons. The author believes that it is no longer used in perfumes, and perhaps no longer manufactured on a commercial scale.
Produced from Toluene plus tertiary-Butyl-chloride and Aluminum chloride in a Friedel-Craft’s reaction to produce the tertiary-Butyl derivative. Nitration with Nitric- plus Sulfuric acids yields the title material.