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ISO-SAFROLE

PROHIBITION · CAP
CAS
94-59-7
EC
—
Material type
other
Canonical source
document derived
Formulation

Usage guidance

Suggested min
—
Suggested max
—
Cost
—
Stock
—
Compatibility tags
orientalgourmandfougerespice-accordroot-beertobacco
How it behaves

Olfactory profile

Family
sweet
Note tendency
Middle
Descriptors
warmsweetfloralanisicspicytenacious

A sweet, warm anise-like aroma with a distinctly licorice and root-beer character. More rounded and sweeter than safrole itself, with a soft balsamic-spicy facet reminiscent of sassafras. Long-lasting on the blotter with a creamy, slightly powdery drydown.AI · claude-opus-4-7

Intensity
7 / 10
Tenacity
7 / 10
Volatility
4 / 10
Members

The rest of this material

Composition, IFRA restriction figures, allergen concentrations and where this material is bought are part of Perfume Foundry’s curated library and need an account. Create one or sign in.

chemicals · No. 2814

Arctander monograph

Perfume and Flavor Chemicals, page 1241.

tenacity · high
warmsweetfloralanisicspicytenacious
MW
162.19
BP
248°C
MP
7°C
Sp.Gr.
—
Refractive n
—
Rotation
—
Appearance

Colorless oily liquid. Solidifies in the cold.

Solubility

Insoluble in water, poorly soluble in propylene glycol and glycerin, soluble in alcohol and oils.

Odor

Warm and sweet, soft, floral-anisic, mildly spicy and tenacious odor. Sweeter, more floral, more anisic, less woody-spicy than Safrole.

Flavor

Sweet, warm, mostly floral taste in concentrations near 30 ppm. Tends to appear perfumey at higher concentrations.

Uses in perfumery

The title material is very well known by name, but hardly ever used as such in perfumery. It serves as an intermediate in the manufacture of Heliotropine, although certain methods avoid this step altogether.

Uses in flavor

Iso-Safrole is not permitted in flavors in the U.S.A., and also banned from food flavors in most other countries.

Production

Produced from Safrole by treatment with potassium or sodium hydroxide in dry state or alcoholic solution, under pressure or at atmospheric pressure.

IFRA Annex I

Found naturally in

Natural complex substances (NCSs) in which this material typically occurs.

NCSBotanicalTypical %
SASSAFRAS BARK OILSassafras albidum (Nutt.) Nees92%
OCATEA CYMBARUM OILOcotea cymbarum Kunth92%
CAMPHOR OIL, BROWNCinnamomum camphora (L.) J.Presl80%
MACE OILMyristica fragrans Houtt.1.7%
NUTMEG OIL, DISTILLEDMyristica fragrans Houtt.1.5%
CINNAMON BARK EXTRACTCinnamomum zeylanicum Blume0.2%
CUBEB OILPiper cubeba L. f.0.05%
LITSEA CUBEBA OILLitsea Cubeba(Lour.) Pers.0.05%
RAVENSARA AROMATICA OILRavansara aromatica Sonn. (v. anisata)0.03%
Identity
Aliases · 20
120-58-194-58-61,2-Methylenedioxy-4-propenylbenzene1,3-Benzodioxole, 5-(1-propenyl)-1,3-Benzodioxole, 5-(2-propenyl)-1,3-Benzodioxole, 5-propyl-3,4-Methylene dioxyallylbenzene3,4-Methylenedioxypropylbenzene4-Allyl-1,2-methylene dioxybenzene5-Allyl-1,3-benzodioxole5-Prop-1-en-1-yl-1,3-benzodioxole5-Propyl-1,3-benzodioxole94-59-7Iso-safroleSafrole, Isosafrole and Dihydrosafrole1,2-Methylenedioxy-4-propylene benzene3,4-Methylenedioxy propylene benzene4-Propenylcatechol methylene ether4-Propylene-1,2-methylenedioxy benzeneSafrol
Compliance note. Restriction data is sourced directly from IFRA publications and preserved with its document excerpt. Perfume Foundry is a compliance-support tool — not a substitute for a qualified safety assessor (CPSR / PIF).